Parasitic load and histopathology of cutaneous lesions, lymph node, spleen, and liver from BALB/c and C57BL/6 mice infected with Leishmania mexicana.

@article{Torrentera2002ParasiticLA,
  title={Parasitic load and histopathology of cutaneous lesions, lymph node, spleen, and liver from BALB/c and C57BL/6 mice infected with Leishmania mexicana.},
  author={Fabiola Aguilar Torrentera and M Alexandra Lambot and Jon D Laman and Marjan van Meurs and R{\'o}bert Kiss and Jean-Christophe No{\"e}l and Yves Carlier},
  journal={The American journal of tropical medicine and hygiene},
  year={2002},
  volume={66 3},
  pages={273-9}
}
The course of infection, parasitic loads, and histopathology of cutaneous lesions, draining lymph node, spleen, and liver were compared in BALB/c and C57BL/6 mice over a period of 34 weeks after inoculation in footpad with promastigotes of a Leishmania mexicana reference strain. The results show that the primary footpad lesions first present a 12-week phase that develops similarly in both strains of mice. Thereafter, a cutaneous and visceral dissemination of L. mexicana parasites occurs in BALB… CONTINUE READING

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