Parasite maturation and host serum iron influence the labile iron pool of erythrocyte stage Plasmodium falciparum

@article{Clark2013ParasiteMA,
  title={Parasite maturation and host serum iron influence the labile iron pool of erythrocyte stage Plasmodium falciparum},
  author={M. Clark and N. Fisher and R. Kasthuri and Carla Cerami Hand},
  journal={British Journal of Haematology},
  year={2013},
  volume={161}
}
Iron is a critical and tightly regulated nutrient for both the malaria parasite and its human host. The importance of the relationship between host iron and the parasite has been underscored recently by studies showing that host iron supplementation may increase the risk of falciparum malaria. It is unclear what host iron sources the parasite is able to access. We developed a flow cytometry‐based method for measuring the labile iron pool (LIP) of parasitized erythrocytes using the nucleic acid… Expand
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