Parasite-induced permeation of nucleosides in Plasmodium falciparum malaria.

  title={Parasite-induced permeation of nucleosides in Plasmodium falciparum malaria.},
  author={Joanne M Upston and Annette M. Gero},
  journal={Biochimica et biophysica acta},
  volume={1236 2},
A mechanism which mediates the transport of the nonphysiological nucleoside, L-adenosine, was demonstrated in Plasmodium falciparum infected erythrocytes and naturally released merozoites. L-Adenosine was not a substrate for influx in freed intraerythrocytic parasites or in normal human erythrocytes nor was L-adenosine transported in a variety of cell types including other parasitic protozoa such as Crithidia luciliae, Trichomonas vaginalis, Giardia intestinalis, or the mammalian cells, Buffalo… CONTINUE READING