Parasite genomics: Screening for the essentials

  • Ashley York
  • Published 2017 in Nature Reviews Microbiology


The targeted degradation of foreign nucleic acids by type III CRISPR–Cas systems is mediated by the multisubunit Csm interference complex. In addition, the CRISPR-associated protein Csm6 ribonuclease, which does not form part of the Csm complex, degrades foreign RNAs to provide full immunity, but how these two processes are linked is unknown. Now, two new… (More)
DOI: 10.1038/nrmicro.2017.94


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