Parasite density and impaired biochemical/hematological status are associated with severe clinical aspects of canine visceral leishmaniasis.

@article{Reis2006ParasiteDA,
  title={Parasite density and impaired biochemical/hematological status are associated with severe clinical aspects of canine visceral leishmaniasis.},
  author={Alexandre B. Reis and Olindo Assis Martins-Filho and Andr{\'e}a Teixeira-Carvalho and Maria Carvalho and Wilson Mayrink and Jo{\~a}o Carlos França-Silva and Rodolfo Cordeiro Giunchetti and Odair Genaro and Rodrigo Corr{\^e}a-Oliveira},
  journal={Research in veterinary science},
  year={2006},
  volume={81 1},
  pages={68-75}
}
We have performed a detailed investigation in 40 dogs naturally infected with Leishmania infantum (syn. chagasi), subdivided into three groups: asymptomatic (AD = 12), oligosymptomatic (OD = 12) and symptomatic (SD = 16), based on their clinical features. Twenty non-infected dogs (CD) were included as control group. Serological analysis, performed by IFAT and ELISA, demonstrated higher antibodies titers in SD in comparison to the AD. A positive correlation was found between parasite density in… CONTINUE READING