Parasite annexins--new molecules with potential for drug and vaccine development.

@article{Hofmann2010ParasiteAM,
  title={Parasite annexins--new molecules with potential for drug and vaccine development.},
  author={Andreas Hofmann and Asiah Osman and Chiuan Yee Leow and Patrick Driguez and Donald P McManus and Malcolm K Jones},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2010},
  volume={32 11},
  pages={
          967-76
        }
}
In the last few years, annexins have been discovered in several nematodes and other parasites, and distinct differences between the parasite annexins and those of the hosts make them potentially attractive targets for anti-parasite therapeutics. Annexins are ubiquitous proteins found in almost all organisms across all kingdoms.Here, we present an overview of novel annexins from parasitic organisms, and summarize their phylogenetic and biochemical properties, with a view to using them as drug or… CONTINUE READING
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