Corpus ID: 2104751

Parasite Strain Stage Standard Plasmodium falciparum K 1 IEF Chloroquine Trypanosoma brucei

  title={Parasite Strain Stage Standard Plasmodium falciparum K 1 IEF Chloroquine Trypanosoma brucei},
  author={Erastus K. Mwangi and Joseph. M. Keriko and Alex King’ori Machocho and Alphonse W Wanyonyi and Hamisi M Malebo and Sumesh Chander Chhabra and Paul K. Tarus},
Chromatographic separation of the leaves of Teclea trichocarpa (Engl.) Engl. (Rutaceae) used traditionally by Akamba tribe in Kenya yielded three acridone alkaloids, a furoquinoline alkaloid and two triterpenoids. The total extract (methanol) of the leaves of this plant and the isolated compounds were screened for in vitro for cytotoxicity and against parasitic protozoa, Plasmodium falciparum, Trypanosoma brucei rhodesiense, Trypanosoma cruzi and Leishmania donovani. Among the compounds… Expand

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