Paraquat embryotoxicity in the Xenopus laevis cleavage phase.

@article{Vismara2001ParaquatEI,
  title={Paraquat embryotoxicity in the Xenopus laevis cleavage phase.},
  author={C. Vismara and R. Bacchetta and B. Cacciatore and G. Vailati and U. Fascio},
  journal={Aquatic toxicology},
  year={2001},
  volume={55 1-2},
  pages={
          85-93
        }
}
The high Paraquat (PQ, 1-1'-dimethyl-4,4'bipyridylium dichloride) embryotoxicity in Xenopus laevis has been shown to be due to its rapid reduction and instantaneous re-oxidation which produces a reactive oxygen species, ROS. Nevertheless, PQ did not show any effects before hatching, stage 32, which showed a resistance, in early X. laevis development, to oxidative damage. Moreover, in view of its genotoxic properties in several experimental models, we studied PQ in the X. laevis cleavage phase… Expand
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