Paraoxonase Activity and Expression Is Modulated by Therapeutics in Experimental Rat Nonalcoholic Fatty Liver Disease

@inproceedings{Hussein2012ParaoxonaseAA,
  title={Paraoxonase Activity and Expression Is Modulated by Therapeutics in Experimental Rat Nonalcoholic Fatty Liver Disease},
  author={Osamah A Hussein and Jamal M Zidan and K. Abu Jabal and I. Shams and Sergio Szvalb and Masha Grozovski and Ilana Bersudsky and Rachel Karry and Michael Y Aviram},
  booktitle={International journal of hepatology},
  year={2012}
}
Objective. The objective of the present study is to investigate the effect of rosiglitazone, metformin, ezetimibe, and valsartan (alone or in combinations) on paraoxonase (PON) activity and PON-mRNA expression in nonalcoholic fatty liver disease (NAFLD). Methods. 54 Male Sprague-Dawley rats were divided to 9 groups: chow diet group (15 weeks); methionine… CONTINUE READING