Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population.

@article{Slowik2007Paraoxonase2G,
  title={Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population.},
  author={Agnieszka Julia Slowik and Dorota Wloch and Pawel Szermer and Pawel Wolkow and Maciej T Malecki and Joanna Pera and Wojciech Turaj and Tomasz Dziedzic and A Klimkowicz-Mrowiec and Grzegorz Kope{\'c} and Denise A. Figlewicz and Andrzej Szczudlik},
  journal={Cerebrovascular diseases},
  year={2007},
  volume={23 5-6},
  pages={395-400}
}
BACKGROUND Oxidative stress plays a role in atherosclerosis. Human paraoxonase (PON) gene products exhibit antioxidant properties. We studied the significance of the Q192R and M55L polymorphisms of the PON1 gene and the C311S polymorphism of the PON2 gene in different etiologies of ischemic stroke. METHODS One hundred and thirty-six patients with large vessel disease (LVD) stroke, 140 with small vessel disease stroke, 272 with cardioembolic stroke, and their age- and sex-matched controls were… CONTINUE READING

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