Paraneoplastic neurological degenerations: keys to tumour immunity
@article{Albert2004ParaneoplasticND, title={Paraneoplastic neurological degenerations: keys to tumour immunity}, author={M. Albert and R. Darnell}, journal={Nature Reviews Cancer}, year={2004}, volume={4}, pages={36-44} }
Paraneoplastic neurological degenerations (PNDs) are neurological disorders that develop in patients with cancer. PNDs are triggered by an effective antitumour immune response against neuronal antigens that are expressed in cancer cells, which subsequently develops into autoimmune neurodegenerative disease. Studying patients with PND has offered the opportunity to gain unique insights into mechanisms of tumour immunity and has provided the potential to apply this knowledge to patients with… Expand
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