Paraneoplastic encephalomyelopathies: pathology and mechanisms

@article{Mckeon2011ParaneoplasticEP,
  title={Paraneoplastic encephalomyelopathies: pathology and mechanisms},
  author={Andrew Mckeon and Sean J. Pittock},
  journal={Acta Neuropathologica},
  year={2011},
  volume={122},
  pages={381-400}
}
The last three decades have seen major advances in the understanding of paraneoplastic and idiopathic autoimmune disorders affecting the central nervous system (CNS). Neural-specific autoantibodies and their target antigens have been discovered, immunopathology and neuroimaging patterns recognized and pathogenic mechanisms elucidated. Disorders accompanied by autoantibody markers of neural peptide-specific cytotoxic effector T cells [such as anti-neuronal nuclear antibody type 1 (ANNA-1, aka… CONTINUE READING

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