Paraneoplastic cerebellar degeneration with anti‐Yo antibodies – a review

  title={Paraneoplastic cerebellar degeneration with anti‐Yo antibodies – a review},
  author={Anand Venkatraman and Puneet Opal},
  booktitle={Annals of clinical and translational neurology},
The ataxic syndrome associated with Anti-Yo antibody, or Purkinje cell cytoplasmic antibody type 1 (PCA1), is the most common variant of paraneoplastic cerebellar degeneration (PCD). The typical presentation involves the subacute development of pancerebellar deficits with a clinical plateau within 6 months. The vast majority of cases have been reported in women with pelvic or breast tumors. Magnetic resonance imaging of the brain is often normal in the early stages, with cerebellar atrophy seen… CONTINUE READING
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