Paraneoplastic Hypocalcemia Developed in Gastric Cancer Accompanied by Osteoblastic Metastasis


Paraneoplastic syndromes are generally defined as clinical disorders associated with malignant diseases, and hypocalcemia associated with cancer is a rare condition. A woman in her 60s was referred to our hospital for the further examination of massive ascites due to carcinoma of unknown primary origin. She complained of numbness around her lips, and marked hypocalcemia of 5.0 mg/dL was noted. After two courses of chemotherapy, computed tomography showed a decrease in the ascites, and her serum calcium level increased. Although hypocalcemia is a very rare condition in patients with gastric cancer, serum calcium values should be evaluated when neurological symptoms are observed.

DOI: 10.2169/internalmedicine.56.8545

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@inproceedings{Okazaki2017ParaneoplasticHD, title={Paraneoplastic Hypocalcemia Developed in Gastric Cancer Accompanied by Osteoblastic Metastasis}, author={Jun Okazaki and Naoki Muguruma and Shinji Kitamura and Tetsuo Kimura and Koichi Okamoto and Hiroshi Miyamoto and Kazuhiro Kishi and Yoshimi Bando and Takeshi Kondo and Itsuro Endo and Masahiro Abe and Tetsuji Takayama}, booktitle={Internal medicine}, year={2017} }