Paramyxovirus evasion of innate immunity: Diverse strategies for common targets.

  title={Paramyxovirus evasion of innate immunity: Diverse strategies for common targets.},
  author={Michelle D Audsley and Gregory William Moseley},
  journal={World journal of virology},
  volume={2 2},
The paramyxoviruses are a family of > 30 viruses that variously infect humans, other mammals and fish to cause diverse outcomes, ranging from asymptomatic to lethal disease, with the zoonotic paramyxoviruses Nipah and Hendra showing up to 70% case-fatality rate in humans. The capacity to evade host immunity is central to viral infection, and paramyxoviruses have evolved multiple strategies to overcome the host interferon (IFN)-mediated innate immune response through the activity of their IFN… CONTINUE READING
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