Paramyxovirus RNA editing and the requirement for hexamer genome length.

  title={Paramyxovirus RNA editing and the requirement for hexamer genome length.},
  author={St{\'e}phane Hausmann and Judith Jacques and Daniel Kolakofsky},
  volume={2 10},
Paramyxoviruses cotranscriptionally edit their P gene mRNA by the programmed insertion of G residues into a short G run contained within a larger purine run, via pseudo-templated transcription. The templates for paramyxovirus transcription are genome nucleocapsids in which each nucleoprotein subunit is associated with 6 nt, and only genomes whose lengths are multiples of 6 are found naturally or are replicated efficiently in transfected cell systems. We have examined the effect of varying total… CONTINUE READING


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