Parametric evaluation of the development of sensitization to the effects of morphine on locomotor activity.

@article{Powell2001ParametricEO,
  title={Parametric evaluation of the development of sensitization to the effects of morphine on locomotor activity.},
  author={Kelly R. Powell and Stephen G. Holtzman},
  journal={Drug and alcohol dependence},
  year={2001},
  volume={62 1},
  pages={83-90}
}
Animals repeatedly administered drugs of abuse often become more sensitive to their effects. It has been proposed that this behavioral sensitization may serve as a useful model for changes that may underlie the etiology and maintenance of drug-seeking behavior. This study was designed to determine systematically some of the conditions of drug exposure under… CONTINUE READING