Parametric Analysis of fMRI Data Using Linear Systems Methods

@article{Cohen1997ParametricAO,
  title={Parametric Analysis of fMRI Data Using Linear Systems Methods},
  author={Mark S. Cohen},
  journal={NeuroImage},
  year={1997},
  volume={6},
  pages={93-103}
}
  • Mark S. Cohen
  • Published 1 August 1997
  • Computer Science, Medicine
  • NeuroImage
Using a model of the functional MRI (fMRI) impulse response based on published data, we have demonstrated that the form of the fMRI response to stimuli of freely varied timing can be modeled well by convolution of the impulse response with the behavioral stimulus. The amplitudes of the responses as a function of parametrically varied behavioral conditions are fitted well using a piecewise linear approximation. Use of the combined model, in conjunction with correlation analysis, results in an… 
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