Parametrial boost using midline shielding results in an unpredictable dose to tumor and organs at risk in combined external beam radiotherapy and brachytherapy for locally advanced cervical cancer.

@article{Fenkell2011ParametrialBU,
  title={Parametrial boost using midline shielding results in an unpredictable dose to tumor and organs at risk in combined external beam radiotherapy and brachytherapy for locally advanced cervical cancer.},
  author={Louis Fenkell and Marianne S Assenholt and S. R. K. Nielsen and Christine Haie-meder and Richard Poetter and Jacob Christian Lindegaard and Kari Tanderup},
  journal={International journal of radiation oncology, biology, physics},
  year={2011},
  volume={79 5},
  pages={1572-9}
}
PURPOSE Midline-blocked boost (MBB) fields are frequently used in the treatment of locally advanced cervical cancer. The purpose of this study was to evaluate the dose contribution from MBBs to tumor and organs at risk. METHODS AND MATERIALS Six patients with locally advanced cervical cancer (IIB-IIIB) treated with definitive chemoradiotherapy and magnetic resonance imaging (MRI)-guided brachytherapy were analyzed. A three-phase plan was modeled: 45 Gy (1.8 Gy per fraction) four-field box, 9… CONTINUE READING

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