Parameters for successful pig islet isolation as determined using 68 specific-pathogen-free miniature pigs.


BACKGROUND Islet cell transplantation is a novel therapeutic modality for the cure of diabetes. Pig islet cells are an attractive substitute for human islet cells; however, they are known to be particularly difficult to isolate because of a weak islet capsule and a tendency to be fragmented during enzymatic digestion. Therefore, parameters favoring… (More)
DOI: 10.1111/j.1399-3089.2008.00504.x


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