Parameter estimation in stochastic biochemical reactions.

  title={Parameter estimation in stochastic biochemical reactions.},
  author={Stefan Reinker and Rachel MacKay Altman and Jens Timmer},
  journal={Systems biology},
  volume={153 4},
Gene regulatory, signal transduction and metabolic networks are major areas of interest in the newly emerging field of systems biology. In living cells, stochastic dynamics play an important role; however, the kinetic parameters of biochemical reactions necessary for modelling these processes are often not accessible directly through experiments. The problem of estimating stochastic reaction constants from molecule count data measured, with error, at discrete time points is considered. For… CONTINUE READING
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