Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.

@article{Paolini1996ParamagneticRI,
  title={Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.},
  author={M. Paolini and Laura Pozzetti and Gian Franco Pedulli and Maurizio Cipollone and Renata Mesirca and G. Cantelli-forti},
  journal={Journal of investigative medicine : the official publication of the American Federation for Clinical Research},
  year={1996},
  volume={44 8},
  pages={470-3}
}
BACKGROUND Despite the increasing interest in the role of oxygen radicals on human degenerative disorders including cancer, oxidative stress status is not yet measurable in vivo, largely precluding clinical application. Limited semi-quantitative assays of damage to broad classes of biomolecules such as lipids, proteins, and DNA are currently available. The detection of radicals in humans by a whole-body electron paramagnetic resonance (EPR) technique has not yet been developed, although this… CONTINUE READING