Parallels between neuron and lens fiber cell structure and molecular regulatory networks.

@article{Frederikse2012ParallelsBN,
  title={Parallels between neuron and lens fiber cell structure and molecular regulatory networks.},
  author={Peter H. Frederikse and Chinnaswamy Kasinathan and Norman J. Kleiman},
  journal={Developmental biology},
  year={2012},
  volume={368 2},
  pages={255-60}
}
Studies over the past fifty years have identified extensive similarities between neurons and elongated fiber cells that make up in the interior of the ocular lens. Electron micrographs showed parallels in the organization of their intracellular vesicle transport machinery and between lens fiber cell lateral protrusions and dendritic spines. Consistent with those observations, a number of gene products first characterized as highly neuron-preferred in their expression were also demonstrated in… CONTINUE READING

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