Parallel reduction in expression of the eye development gene hedgehog in separately derived cave populations of the amphipod Gammarus minus

@article{Aspiras2012ParallelRI,
  title={Parallel reduction in expression of the eye development gene hedgehog in separately derived cave populations of the amphipod Gammarus minus},
  author={Ariel C. Aspiras and R. Prasad and Daniel W. Fong and David B. Carlini and David R. Angelini},
  journal={Journal of Evolutionary Biology},
  year={2012},
  volume={25}
}
Caves provide excellent settings to examine evolutionary questions. Subterranean environments are characterized by similar and consistent conditions. Cave‐adapted species often share characteristics such as diminished pigmentation, elongated limbs and reduced or absent eyes. Relatively little is known about the evolution and development of troglomorphic traits in invertebrates. In this study, we compare expression of the eye development genes hedgehog, pax6, sine oculis and dachshund in… Expand
Embryonic origin and genetic basis of cave associated phenotypes in the isopod crustacean Asellus aquaticus
TLDR
This study uses an invertebrate model system, the freshwater isopod crustacean, Asellus aquaticus, to examine whether adult differences between cave and surface dwelling individuals first appear during embryonic development, and finds that differences in pigmentation, eye formation, and number of segments of antenna II were all present by the end of embryonic development. Expand
Common Genetic Basis of Eye and Pigment Loss in Two Distinct Cave Populations of the Isopod Crustacean Asellus aquaticus.
TLDR
It is found that the same genomic regions are responsible for eye and pigment loss and that at least one of the genes causing pigment loss is the same in both cave populations. Expand
Parallel reduction in expression, but no loss of functional constraint, in two opsin paralogs within cave populations of Gammarus minus (Crustacea: Amphipoda)
TLDR
The concordantly lowered expression level of both opsin genes in cave populations of G. minus compared to sister surface populations, combined with evidence for persistent purifying selection in the cave populations, is consistent with an unspecified pleiotropic function of opsin proteins. Expand
Sexually dimorphic gene expression in the lateral eyes of Euphilomedes carcharodonta (Ostracoda, Pancrustacea)
TLDR
It is shown here that expression changes of a handful of developmental genes may underlie the radical difference in a dimorphic character in the Pancrustacea. Expand
Transcriptome-Wide Differential Gene Expression in Bicyclus anynana Butterflies: Female Vision-Related Genes Are More Plastic.
Vision is energetically costly to maintain. Consequently, over time many cave-adapted species downregulate the expression of vision genes or even lose their eyes and associated eye genes entirely.Expand
Repeated eye reduction events reveal multiple pathways to degeneration in a family of marine snails
TLDR
It is estimated eye loss has evolved at least seven times within Solariellidae, in at least three different ways: characters such as pigmentation loss, obstruction of eye aperture, and “lens” degeneration can occur in any order. Expand
Developmental evolution of the visual system in the cave-adapted small carrion beetle Ptomaphagus hirtus
TLDR
The morphology and organization of the reduced P. hirtus eyelet are explored using immunohistochemistry, laser scanning microscopy, and ultrastructural imaging approaches, demonstrating that the adult eyelet lacks ommatidial subdivision and has a thick, clear cuticular lens. Expand
Rapid evolution of troglomorphic characters suggests selection rather than neutral mutation as a driver of eye reduction in cave crabs
TLDR
The temporal pattern of character change following the transition to subterranean life was indistinguishable for constructive and reductive traits, characterized by an immediate onset and rapid evolutionary change. Expand
Evolution of eye development in the darkness of caves: adaptation, drift, or both?
TLDR
It is concluded that both genetic drift and direct and indirect selection occurred together during the loss of eyes in cave animals, and some future directions of research to better understand adaptation to total darkness are identified. Expand
The transcriptomes of cave and surface populations of Gammarus minus (Crustacea: Amphipoda) provide evidence for positive selection on cave downregulated transcripts
TLDR
RNA-Seq was conducted on one pair of morphologically distinct sister populations inhabiting surface and cave habitats to identify genes that were differentially expressed in the two populations, as well as to compare levels and patterns of genetic variation within and between populations. Expand
...
1
2
...

References

SHOWING 1-10 OF 58 REFERENCES
Genetic basis of eye and pigment loss in the cave crustacean, Asellus aquaticus
TLDR
This work shows the potential of Asellus for studying the extremes of parallel and convergent evolution—spanning comparisons within populations to comparisons between vertebrate and arthropod systems. Expand
Adaptive evolution of eye degeneration in the Mexican blind cavefish.
  • W. Jeffery
  • Biology, Medicine
  • The Journal of heredity
  • 2005
TLDR
It is concluded that eye degeneration in cavefish may be caused by adaptive evolution and pleiotropy, and a key discovery is that Hedgehog midline signaling is expanded and inhibits eye formation by inducing lens apoptosis in Cavefish embryos. Expand
Hedgehog signalling controls eye degeneration in blind cavefish
TLDR
It is shown that sonic hedgehog and tiggy-winkle hedgehog gene expression is expanded along the anterior embryonic midline in several different cavefish populations, supporting the role of hh signalling in the evolution of cavefish eye regression. Expand
Chance caught on the wing: cis-regulatory evolution and the origin of pigment patterns in Drosophila
TLDR
It is shown that the evolution of this spot involved modifications of an ancestral cis-regulatory element of the yellow pigmentation gene, which has gained multiple binding sites for transcription factors that are deeply conserved components of the regulatory landscape controlling wing development. Expand
Morphological Evolution of the Amphipod Gammarus minus in Caves: Quantitative Genetic Analysis
TLDR
It is argued that the observed patterns agree with the hypothesis of indirect selection with negative pleiotropy and that these patterns are not in accord with the hypotheses that the reduction in eye size in cave populations results from accumulation of neutral mutations alone. Expand
Parallel evolution of Pitx1 underlies pelvic reduction in Scottish threespine stickleback (Gasterosteus aculeatus).
TLDR
It is shown that the Pitx1 locus is also likely to underlie pelvic reduction in a Scottish population of threespine stickleback, which has apparently evolved pelvic reduction under a different selection regime than the North American populations. Expand
Evolution of yellow Gene Regulation and Pigmentation in Drosophila
TLDR
Comparison of the regulation of the yellow gene, which is required for melanization, among distantly related Drosophila species with different pigment patterns and the phenotypic effects of evolutionary changes in Yellow expression are found to depend on epistatic interactions with other genes. Expand
Molecular genetic variation and population structure in morphologically differentiated cave and surface populations of the freshwater amphipod Gammarus minus
TLDR
Overall these data indicate limited gene flow among populations and suggest that the cave populations sampled in this study are prone to bottlenecks, possibly due to larger temperature fluctuations and more frequent incidence of drought conditions associated with these particular cave habitats. Expand
Differential requirements for the Pax6(5a) genes eyegone and twin of eyegone during eye development in Drosophila.
TLDR
It is demonstrated that both eyg and toe encode transcriptional repressors, are expressed in identical patterns but at significantly different levels and that Eyg makes differential use of several domains when compared to Toe and that the number of repressor domains also differs between the two Pax6(5a) homologs. Expand
Repeated morphological evolution through cis-regulatory changes in a pleiotropic gene
TLDR
It is shown that a male wing pigmentation pattern involved in courtship display has been gained and lost multiple times in a Drosophila clade, demonstrating how the functional diversification of the modular CREs of pleiotropic genes contributes to evolutionary novelty and the independent evolution of morphological similarities. Expand
...
1
2
3
4
5
...