Parallel control of mechanosensory hair cell orientation by the PCP and Wnt pathways

@inproceedings{Acedo2019ParallelCO,
  title={Parallel control of mechanosensory hair cell orientation by the PCP and Wnt pathways},
  author={Joaquin Navajas Acedo and Matthew G. Voas and Richard H.L. Alexander and Thomas E. Woolley and Jay R Unruh and Hua Li and Cecilia B Moens and Tatjana Piotrowski},
  year={2019}
}
Cell polarity plays a crucial role during development of vertebrates and invertebrates. Planar Cell Polarity (PCP) is defined as the coordinated polarity of cells within a tissue axis and is essential for processes such as gastrulation, neural tube closure or hearing. Wnt ligands can be instructive or permissive during PCP-dependent processes, and Wnt pathway mutants are often classified as PCP mutants due to the complexity and the similarities between their phenotypes. Our studies of the… CONTINUE READING

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