Parallel Arms Races between Garter Snakes and Newts Involving Tetrodotoxin as the Phenotypic Interface of Coevolution

@article{Brodie2005ParallelAR,
  title={Parallel Arms Races between Garter Snakes and Newts Involving Tetrodotoxin as the Phenotypic Interface of Coevolution},
  author={Edmund D. Brodie and Chris R. Feldman and Charles T Hanifin and Jeffrey E. Motychak and Daniel G. Mulcahy and Becky L. Williams and Edmund D. Brodie},
  journal={Journal of Chemical Ecology},
  year={2005},
  volume={31},
  pages={343-356}
}
Parallel “arms races” involving the same or similar phenotypic interfaces allow inference about selective forces driving coevolution, as well as the importance of phylogenetic and phenotypic constraints in coevolution. Here, we report the existence of apparent parallel arms races between species pairs of garter snakes and their toxic newt prey that indicate independent evolutionary origins of a key phenotype in the interface. In at least one area of sympatry, the aquatic garter snake… Expand
The geographic mosaic in parallel: matching patterns of newt tetrodotoxin levels and snake resistance in multiple predator-prey pairs.
TLDR
Overall, the three species of newts appear to be engaged in a TTX-mediated arms race with Th. Expand
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Evolution typically arrives at convergent phenotypic solutions to common challenges of natural selection. However, diverse molecular and physiological mechanisms may generate phenotypes that appearExpand
Predictably Convergent Evolution of Sodium Channels in the Arms Race between Predators and Prey.
TLDR
Trade-offs between the fundamental role of NaV1 proteins in selective permeability of Na+ and their ability to resist binding by TTX generate a highly constrained adaptive landscape at the level of the protein. Expand
Phenotypic variation of toxin levels in a chemically defended amphibian: The ecological and evolutionary significance of tetrodotoxin
TLDR
The California newt (Taricha torosa) was evaluated in streams of the Santa Monica Mountains, demonstrating a striking ecological role for T. torosa and TTX, and implying that the loss of this amphibian in the study system may have wide-reaching ecological consequences. Expand
Evolutionary GEM: The Evolutionary Arms Race of Garter Snakes and Newts
TLDR
While both adaptations come with costs, the coexistence of newt and garter snake imposes reciprocal selective pressure that drives this arms race. Expand
Evolutionary history of a complex adaptation: Tetrodotoxin resistance in salamanders
  • C. Hanifin, W. Gilly
  • Biology, Medicine
  • Evolution; international journal of organic evolution
  • 2015
TLDR
The results suggest that exaptation has played a role in the evolution of the TTX‐bearing phenotype and provide empirical evidence that complex physiological adaptations can arise through the accumulation of beneficial mutations in the coding region of conserved proteins. Expand
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