Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease.

@article{ParrBrownlie2009ParafascicularTN,
  title={Parafascicular thalamic nucleus activity in a rat model of Parkinson's disease.},
  author={Louise C. Parr-Brownlie and Stacey L. Poloskey and Debra A Bergstrom and Judith R. Walters},
  journal={Experimental neurology},
  year={2009},
  volume={217 2},
  pages={269-81}
}
Parkinson's disease is associated with increased oscillatory firing patterns in basal ganglia output, which are thought to disrupt thalamocortical activity. However, it is unclear how specific thalamic nuclei are affected by these changes in basal ganglia activity. The thalamic parafascicular nucleus (PFN) receives input from basal ganglia output nuclei and directly projects to the subthalamic nucleus (STN), striatum and cortex; thus basal ganglia-mediated changes on PFN activity may further… CONTINUE READING