Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium.

@article{Bers1993ParadoxicalTP,
  title={Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium.},
  author={Donald M. Bers and Rosana Almada Bassani and Jos{\'e} Wilson Magalh{\~a}es Bassani and St{\'e}phane Baudet and Larry V. Hryshko},
  journal={Journal of molecular and cellular cardiology},
  year={1993},
  volume={25 9},
  pages={1047-57}
}
Rest interval dependent changes in contractile force (rest decay and rest potentiation) were studied in rabbit, rat and ferret ventricular muscle and myocytes. The SR Ca content was assessed by rapid cooling contractures or caffeine induced contractures. Intracellular Ca transients, action potentials and Ca current were also recorded. Rest decay of twitches in rabbit ventricle are roughly paralleled by a decline in SR Ca content. Rat ventricle exhibits primarily rest potentiation, which is not… CONTINUE READING