Paradoxical structural effects in the unilaterally denervated spontaneously hypertensive rat kidney.

OBJECTIVE To determine the effects of chronic denervation on renal vascular structure and function in young adult spontaneously hypertensive rats (SHRs). DESIGN Unilateral renal denervation (SHRUDx) or sham-operation (SHRS) was performed in SHRs at 6 weeks of age. At 10 weeks, rats were allocated to one of three procedures designed to examine renal… CONTINUE READING