Paradoxical sleep deprivation and the immobility response in the rat: effects of desipramine and phentolamine.

@article{Luijtelaar1985ParadoxicalSD,
  title={Paradoxical sleep deprivation and the immobility response in the rat: effects of desipramine and phentolamine.},
  author={Egidius L J M van Luijtelaar and Anton M. L. Coenen},
  journal={Sleep},
  year={1985},
  volume={8 1},
  pages={49-55}
}
A series of experiments was conducted on the presumption that instrumental deprivation of paradoxical sleep (PS) has an effect comparable with that of antidepressant drug treatment in a behavioral paradigm, Porsolt's forced swim test. After long-term PS deprivation, we studied the duration of immobility, which can be markedly reduced by antidepressant drugs, using both the platform and the pendulum technique. In addition to a small common effect for PS deprivation, differences confirming the… CONTINUE READING