Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection.

@article{Breen2004ParadoxicalRD,
  title={Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection.},
  author={Ronan Angus MacCormick Breen and Catherine Jane Smith and Henry V Bettinson and Susan A. Dart and Bryant Bannister and MargaretA. Johnson and Marc Caeroos Isaac Lipman},
  journal={Thorax},
  year={2004},
  volume={59 8},
  pages={
          704-7
        }
}
BACKGROUND It has been suggested that deterioration of tuberculosis (TB) during appropriate treatment, termed a paradoxical reaction (PR), is more common and severe in HIV positive individuals on highly active antiretroviral therapy (HAART). METHOD A study was undertaken to determine the frequency of PR and its associated features in a population of HIV+TB+ patients and a similar sized group of HIV-TB+ individuals. RESULTS PR occurred in 28% of 50 HIV+TB+ patients and 10% of 50 HIV-TB… CONTINUE READING

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