Paradoxical increase in uric acid level with allopurinol use in pyrazinamide-induced hyperuricaemia.


We report the case of a 36-year-old man with psoriatic arthritis and miliary tuberculosis, whose serum uric acid (SUA) level increased after the initiation of antituberculosis treatment, which included pyrazinamide. Most strikingly and paradoxically, the patient's SUA level increased after treatment with allopurinol. On cessation of allopurinol, his SUA… (More)
DOI: 10.11622/smedj.2013097


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