Paradoxical immune-mediated inflammation in inflammatory bowel disease patients receiving anti-TNF-α agents.

@article{Fiorino2014ParadoxicalII,
  title={Paradoxical immune-mediated inflammation in inflammatory bowel disease patients receiving anti-TNF-α agents.},
  author={Gionata Fiorino and Silvio Danese and Benjamin Pariente and Matthieu Allez},
  journal={Autoimmunity reviews},
  year={2014},
  volume={13 1},
  pages={15-9}
}
Reports of autoimmune diseases, including psoriasis- and dermatitis-like skin reactions with anti-tumor necrosis factor-α (TNF-α), are increasing, likely a reflection of the growing use of these agents. This paradoxical phenomenon can no longer be considered rare, with some studies providing incidence estimates of greater than 10%. This paradoxical inflammation has been reported in patients receiving treatment with anti-TNF-α agents for a variety of inflammatory conditions, including… CONTINUE READING
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