Paradoxical aggravation of vasospasm with papaverine infusion following aneurysmal subarachnoid hemorrhage. Case report.

@article{Clyde1996ParadoxicalAO,
  title={Paradoxical aggravation of vasospasm with papaverine infusion following aneurysmal subarachnoid hemorrhage. Case report.},
  author={B. Clyde and A. Firlik and A. Kaufmann and M. Spearman and H. Yonas},
  journal={Journal of neurosurgery},
  year={1996},
  volume={84 4},
  pages={
          690-5
        }
}
Reports of intraarterial papaverine infusion as treatment for cerebral vasospasm are few and documented complications are uncommon. The authors report the case of a patient with paradoxical aggravation of cerebral arterial narrowing during selective intraarterial papaverine infusion intended to treat vasospasm following aneurysmal subarachnoid hemorrhage (SAH). A 48-year-old man presented to the authors' service with symptomatic vasospasm 10 days after experiencing an SAH. The ruptured anterior… Expand
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Intra-Arterial Nimodipine Infusion for Cerebral Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage
  • W. Cho, H. Kang, +6 authors M.H. Han
  • Medicine
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  • 2011
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In this preliminary anecdotal series of 12 patients who were candidates for balloon angioplasty, vasospasm was treated instead with intra-arterial papaverine, and marked angiographic reversal of the arterial narrowing following papaversine infusion and dramatic reversal of profound neurological deficits were shown. Expand
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Papaverine was effective in dilating narrowed arteries in most patients with symptomatic vasospasm caused by subarachnoid hemorrhage with encouraging clinical results with no recurrence of neurologic deterioration in those patients who responded well to papaverine. Expand
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