Paradigm shifts in heart-failure therapy--a timeline.

  title={Paradigm shifts in heart-failure therapy--a timeline.},
  author={Chana A Sacks and John Adams Jarcho and Gregory D. Curfman},
  journal={The New England journal of medicine},
  volume={371 11},
W the publication of the PARADIGM-HF trial in the Journal (pages 993–1004) we may be entering a new era of treatment for heart failure with reduced ejection fraction. To provide a historical perspective on the beginning of this new epoch, we constructed an interactive timeline (available with the full text of this article at of 26 randomized, controlled trials in heart-failure treatment that have been published in the Journal since 1986. Each of these articles — some demonstrating… CONTINUE READING
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