Paracrine signaling through plasma membrane hemichannels.

Abstract

Plasma membrane hemichannels composed of connexin (Cx) proteins are essential components of gap junction channels but accumulating evidence suggests functions of hemichannels beyond the communication provided by junctional channels. Hemichannels not incorporated into gap junctions, called unapposed hemichannels, can open in response to a variety of signals… (More)
DOI: 10.1016/j.bbamem.2012.07.002

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