Paracrine regulation of growth hormone secretion by estrogen in women.

@article{Birzniece2010ParacrineRO,
  title={Paracrine regulation of growth hormone secretion by estrogen in women.},
  author={V. Birzniece and A. Sata and Surya S. Sutanto and K. Ho},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 8},
  pages={
          3771-6
        }
}
  • V. Birzniece, A. Sata, +1 author K. Ho
  • Published 2010
  • Biology, Medicine
  • The Journal of clinical endocrinology and metabolism
CONTEXT Paracrine regulation is emerging as a discrete control mechanism in the endocrine system. In hypogonadal men, stimulation of GH secretion by testosterone requires prior aromatization to estradiol, a paracrine effect unmasked by central estrogen receptor blockade with tamoxifen. In hypogonadal women, estrogen replacement via a physiological non-oral route fails to enhance GH secretion, indicating an absence of an endocrine effect. The aim was to investigate whether local estrogens… Expand
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