Paracrine control of tissue regeneration and cell proliferation by Caspase-3

  title={Paracrine control of tissue regeneration and cell proliferation by Caspase-3},
  author={Karen Boland and Lorna Flanagan and J H M Prehn},
  booktitle={Cell Death and Disease},
Executioner caspases such as Caspase-3 and Caspase-7 have long been recognised as the key proteases involved in cell demolition during apoptosis. Caspase activation also modulates signal transduction inside cells, through activation or inactivation of kinases, phosphatases and other signalling molecules. Interestingly, a series of recent studies have demonstrated that caspase activation may also influence signal transduction and gene expression changes in neighbouring cells that themselves did… CONTINUE READING


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