Paracetamol poisoning and the kidney.

  title={Paracetamol poisoning and the kidney.},
  author={Alan F. Jones and John Allister Vale},
  journal={Journal of clinical pharmacy and therapeutics},
  volume={18 1},
Nephrotoxicity is less common than hepatotoxicity in paracetamol overdose but renal tubular damage and acute renal failure occur even in the absence of hepatotoxicity. It is possible that antidotal therapy with agents such as N-acetylcysteine may not prevent renal toxicity and, indeed, on the basis of animal work, may actually potentiate tubular damage. Careful clinical attention should be paid to renal function in patients poisoned with paracetamol. 


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