Paracetamol for the treatment of patent ductus arteriosus in preterm neonates: a systematic review and meta-analysis.

@article{Terrin2016ParacetamolFT,
  title={Paracetamol for the treatment of patent ductus arteriosus in preterm neonates: a systematic review and meta-analysis.},
  author={Gianluca Terrin and Francesca Conte and Mehmet Yekta Oncel and Antonella Scipione and Patrick McNamara and Sinno H P Simons and Rahul Sinha and Omer Erdeve and Kadir Şerafettin Tekgunduz and Mustafa Doğan and Irena Kessel and Cathy Hammerman and Erez Nadir and Sadik Yurttutan and Bonny Jasani and Serdar Alan and Francesco Manguso and Mario De Curtis},
  journal={Archives of disease in childhood. Fetal and neonatal edition},
  year={2016},
  volume={101 2},
  pages={F127-36}
}
OBJECTIVES We performed a systematic review and meta-analysis of all the available evidence to assess the efficacy and safety of paracetamol for the treatment of patent ductus arteriosus (PDA) in neonates, and to explore the effects of clinical variables on the risk of closure. DATA SOURCE MEDLINE, Scopus and ISI Web of Knowledge databases, using the following medical subject headings and terms: paracetamol, acetaminophen and patent ductus arteriosus. Electronic and manual screening of… CONTINUE READING
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