Paracentric inversion inv(11) (q21q23) in the Netherlands

@article{Madan1990ParacentricII,
  title={Paracentric inversion inv(11) (q21q23) in the Netherlands},
  author={Kamlesh Madan and Math H. E. C. Pieters and L. P. Kuyt and Christi J. van Asperen and Jennie M. Pater and A. J. H. Hamers and Klasien B J Gerssen-Schoorl and Th. W. J. Hustinx and Anton S. P. M. Breed and Jan O. van Hemel and Dominique F. C. M. Smeets},
  journal={Human Genetics},
  year={1990},
  volume={85},
  pages={15-20}
}
We report the result of investigations from 20 families with 72 carriers of the paracentric inversion inv(11)(q21q23) in the Netherlands. There is no increase in the rate of spontaneous abortions among carriers of the inversion or their partners. Also, so far, there are no children with recombinant chromosomes arising from the inversion. It is doubtful whether prenatal diagnosis would be helpful to carriers of this inversion. The results of the genealogy study and geographical distribution are… CONTINUE READING