Paracelsus to parascience: the environmental cancer distraction.

@article{Ames2000ParacelsusTP,
  title={Paracelsus to parascience: the environmental cancer distraction.},
  author={Bruce Nathan Ames and Lois Swirsky Gold},
  journal={Mutation research},
  year={2000},
  volume={447 1},
  pages={
          3-13
        }
}
Entering a new millennium seems a good time to challenge some old ideas, which in our view are implausible, have little supportive evidence, and might best be left behind. In this essay, we summarize a decade of work, raising four issues that involve toxicology, nutrition, public health, and government regulatory policy. (a) Paracelsus or parascience: the dose (trace) makes the poison. Half of all chemicals, whether natural or synthetic, are positive in high-dose rodent cancer tests. These… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 15 times. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 48 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 68 REFERENCES

A comprehensive approach for integration of toxicity and cancer risk assessŽ . ments , Regul

  • M. S. Bogdanffy
  • Toxicol . Pharmacol .
  • 1999

Cattley , Dysregulation of apoptosis by c - myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens

  • A. Ouhtit, S. M. Loughlin, M. L. Kripke, H. N. Ananthaswamy, L. B. Owen-Schaub
  • Mol . Ž . Carcinog .
  • 1999

Cytokines in nongenotoxic hepatoŽ

  • J. Xu, Y. Ju, E. Alt, P. Schmiedeberg
  • carcinogenesis , Carcinogenesis
  • 1999

The effect of folic acid fortification on plasma folate and total homocysteine concentrations

  • J. Selhub, A. G. Bostom, P. W. Wilson, I. H. Rosenberg
  • N . Engl . J . Ž . Med .
  • 1999

DNA oxidation matters : The HPLCEC assay of 8oxodeoxyguanosine and Ž . 8oxoguanine

  • K. J. Pendino
  • Proc . Natl . Acad . Sci . U . S . A .
  • 1998

Similar Papers

Loading similar papers…