Paracellular pathway remodeling enhances sodium secretion by teleost fish in hypersaline environments.


In vertebrate salt-secreting epithelia, Na(+) moves passively down an electrochemical gradient via a paracellular pathway. We assessed how this pathway is modified to allow Na(+) secretion in hypersaline environments. Mummichogs (Fundulus heteroclitus) acclimated to hypersaline [2× seawater (2SW), 64‰] for 30 days developed invasive projections of accessory… (More)
DOI: 10.1242/jeb.117317

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