Paracellular glucose transport plays a minor role in the unanesthetized dog.

  title={Paracellular glucose transport plays a minor role in the unanesthetized dog.},
  author={J. Scott Lane and Edward E. Whang and David A Rigberg and Oscar Joe Hines and David K Kwan and M. J. Zinner and David W. Mcfadden and J. Diamond and Stanley W Ashley},
  journal={The American journal of physiology},
  volume={276 3 Pt 1},
Traditionally, intestinal glucose absorption was thought to occur through active, carrier-mediated transport. However, proponents of paracellular transport have argued that previous experiments neglected effects of solvent drag coming from high local concentrations of glucose at the brush-border membrane. The purpose of this study was to evaluate glucose absorption in the awake dog under conditions that would maximize any contribution of paracellular transport. Jejunal Thiry-Vella loops were… CONTINUE READING


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