Papillomavirus-like particles for serology and vaccine development.

@article{Kirnbauer1996PapillomaviruslikePF,
  title={Papillomavirus-like particles for serology and vaccine development.},
  author={Reinhard Kirnbauer},
  journal={Intervirology},
  year={1996},
  volume={39 1-2},
  pages={54-61}
}
Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases in women worldwide each year. The L1 major capsid protein of papillomaviruses expressed in eukaryotic cells self-assembles into virus-like particles (VLP). VLP are attractive… CONTINUE READING

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