Papillary Cancer of Thyroid in Celiac Disease

  title={Papillary Cancer of Thyroid in Celiac Disease},
  author={Umberto Volta and Olimpia Vincentini and Marco Silano},
  journal={Journal of Clinical Gastroenterology},
Background Celiac disease (CD) has been established as being associated with several thyroid diseases. However, occurrence of thyroid epithelial cancer in celiac patients has been rarely described. Goal We describe the prevalence of thyroid carcinoma detected in a cohort of Italian celiac patients, with the aim to carry out a prospective analysis of the risk of celiac patients to develop thyroid carcinoma. Methods The study population included all CD patients diagnosed at the Collaborating… 

Risk of thyroid cancer in a nationwide cohort of patients with biopsy-verified celiac disease.

It is concluded that, in the Swedish population, there is no increased risk of thyroid cancer in patients with celiac disease, differs from what has been reported in smaller studies in Italy and the United States.

The Risk of Malignancies in Celiac Disease—A Literature Review

A comprehensive review of the current knowledge about the associations between CeD and cancer, focusing in particular on EATL and SBC, two rare but aggressive malignancies are provided.

Coincidence of celiac disease with nongastrointestinal tumors in children

The results suggest a potential association of CD with malignancy nature of CD, however, occurrence of CD may be influenced by various intrinsic and extrinsic factors.

Case Report: Papillary Thyroid Cancer in a Patient with Celiac Disease and Thalassemia Trait

A unique case of papillary thyroid cancer is reported in a patient with celiac disease and thalassemia trait, which is rare in the general population.

Association Between Celiac Disease and Cancer

A considerable number of studies have considered the possible association between CD and neoplasms and an increased risk of malignancies, such as cancers of the gastrointestinal tract and intestinal lymphomas, has been reported.

Association Between CD and Individual Cancers

Enteropathy-associated T cell Lymphoma (EATL) was firstly used to identify the rare form of highgrade T-cell NHL of the upper small intestine, specifically associated with CD.

Does Celiac Disease Ever Travel Alone

A strict gluten-free diet is advised for patients with celiac disease, but the risk of malignancy associated with Celiac disease is not high enough to warrant mass screening of all individuals.

Screening for celiac disease in average-risk and high-risk populations

There is no consensus on whether institution of a gluten-free diet will improve the quality of life in asymptomatic screen-detected celiac disease patients, and active case finding seems to be the most prudent option in most clinical situations.

Does Gluten Intake Influence the Development of Celiac Disease–associated Complications?

The evidence supporting either hypothesis of Celiac disease or the lack of such correlation would instead suggest a less aggressive diagnostic strategy is critically summarized.

Extraintestinal Manifestations of Celiac Disease and Associated Disorders

In several associated diseases, an adequate adherence to a gluten-free diet may slow their evolution, especially if implemented at an early stage, as well as in type-1 diabetes mellitus, thyroid diseases, and malignancy.



Increased Risk of Papillary Thyroid Cancer in Celiac Disease

Among a cohort of patients with celiac disease, an increased risk of papillary carcinoma of the thyroid, standard morbidity ratio of 22.52 (95% confidence interval 14.90–34.04; P < .001), was identified, compared to United States national surveillance data.

Risk of thyroid disease in individuals with celiac disease.

C celiac disease is associated with thyroid disease, and these associations were seen regardless of temporal sequence, which indicates shared etiology and that these individuals are more susceptible to autoimmune disease.

Autoimmune Thyroid Disease and Celiac Disease in Children

The high frequency of autoimmune thyroid disease found among patients with CD, even those on a gluten‐free diet, may justify a thyroid status assessment at diagnosis and at follow‐up evaluation of children with CD.

Prevalence of thyroid disorders in untreated adult celiac disease patients and effect of gluten withdrawal: an Italian multicenter study

The greater frequency of thyroid disease among celiac disease patients justifies a thyroid functional assessment, and in distinct cases, gluten withdrawal may single-handedly reverse the abnormality.

Delayed diagnosis of coeliac disease increases cancer risk

Coeliac patients have an increased risk of developing cancer in relation to the age of diagnosis of CD, and this risk results higher for malignancies of the gastro-intestinal sites.

Clinical and Subclinical Autoimmune Thyroid Disease in Adult Celiac Disease

The occurrence of both clinical and subclinical autoimmune thyroid disease was increased in celiac disease; subclinical thyroid disease indicates regular surveillance.

Autoimmune thyroid diseases and coeliac disease

The association of coeliac disease with autoimmune thyroid disease is not surprising as they share common immunopathogenetic mechanisms, and it is advisable to screen autoimmune thyroid diseases patients for coeliat disease as there is an increased risk for gluten intolerance.

Coeliac disease and autoimmune thyroid disease.

Three patients are described in whom the coexistence of coeliac disease and hypothyroidism led to diagnostic difficulties and delay of treatment.

T cell lymphoma of the thyroid gland in celiac disease.

  • H. Freeman
  • Medicine
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • 2000
A 66-year-old woman with dermatitis herpetiformis and biopsy-defined celiac disease developed a thyroid mass that proved to be a T cell lymphoma that appears to be unique in the setting of Celiac disease.