Paper-based aptamer-antibody biosensor for gluten detection in a deep eutectic solvent (DES)

  title={Paper-based aptamer-antibody biosensor for gluten detection in a deep eutectic solvent (DES)},
  author={Rossella Svigelj and Nicol{\`o} Dossi and Cristian Grazioli and Rosanna Toniolo},
  journal={Analytical and Bioanalytical Chemistry},
  pages={3341 - 3348}
Paper has been widely employed as cheap material for the development of a great number of sensors such as pregnancy tests, strips to measure blood sugar, and COVID-19 rapid tests. The need for new low-cost analytical devices is growing, and consequently the use of these platforms will be extended to different assays, both for the final consumer and within laboratories. This work describes a paper-based electrochemical sensing platform that uses a paper disc conveniently modified with… 

An Effective Label-Free Electrochemical Aptasensor Based on Gold Nanoparticles for Gluten Detection

Nanomaterials can be used to modify electrodes and improve the conductivity and the performance of electrochemical sensors. Among various nanomaterials, gold-based nanostructures have been used as an

Enhancement of Electrochemical Detection of Gluten with Surface Modification Based on Molecularly Imprinted Polymers Combined with Superparamagnetic Iron Oxide Nanoparticles

Novel molecularly imprinted polymers (MIPs) represent a selectively recognized technique for electrochemical detection design. This rapid and simple method prepared via chemical synthesis consists of

Aptasensors versus immunosensors—Which will prevail?

This work reviews the employment of antibodies and aptamers as capture probes in biosensing platforms, addressing the main aspects of biosensor design and mechanism and elaborate on their combined use in hybrid biosensing schemes benefiting from the advantages of each biorecognition element.

Recent Advances in Electrochemical Sensing Strategies for Food Allergen Detection

Food allergy has been indicated as the most frequent adverse reaction to food ingredients over the past few years. Since the only way to avoid the occurrence of allergic phenomena is to eliminate

A portable electrochemiluminescence aptasensor for β-lactoglobulin detection

Cow’s milk allergy is one of the most common food allergies in children with a prevalence of around 2.5%. Milk contains several allergens; the main ones are caseins and β-lactoglobulin (β-LG). At



Paper and Other Fibrous Materials—A Complete Platform for Biosensing Applications

The examined classical and alternative mathematical models provide a powerful tool for bioanalytical device designing for the multiple steps required in biosensing platforms.

Eco-friendly electrochemical lab-on-paper for heavy metal detection

A disposable electrochemical lateral flow paper-based sensing device for heavy metal detection and quantification of lead and cadmium in aqueous samples is demonstrated, being a promising tool for new point-of-care applications in environmental monitoring, public health, and food safety.

Novel paper-based electroanalytical tools for food surveillance

  • S. Cinti
  • Engineering
    Analytical and Bioanalytical Chemistry
  • 2019
The development of a miniaturized biosensor realized on copy paper for the quantification of ethanol in commercial beers, and the measurement of ascorbic acid in food supplements within printed electronics supports are discussed.

Electrochemical detection for paper-based microfluidics.

This study shows the successful integration of paper-based microfluidics and electrochemical detection as an easy-to-use, inexpensive, and portable alternative for point of care monitoring.

An Effective Gluten Extraction Method Exploiting Pure Choline Chloride-Based Deep Eutectic Solvents (ChCl-DESs)

AbstractGluten analysis is still affected by the lack of an efficient and universal extraction solvent for gliadin, i.e., the prolamine fraction of gluten which is the analytical target used to