Panusin represents a new family of &bgr;‐defensin‐like peptides in invertebrates

  title={Panusin represents a new family of &bgr;‐defensin‐like peptides in invertebrates},
  author={V. Montero-Alejo and G. Corzo and Javier Porro-Suard{\'i}az and Z. Pardo-Ru{\'i}z and E. Perera and L. Rodr{\'i}guez-Viera and Gabriela S'anchez-D'iaz and E. Hern{\'a}ndez-Rodr{\'i}guez and Carlos {\'A}lvarez and S. Peigneur and J. Tytgat and R. Perdomo-Morales},
  journal={Developmental and Comparative Immunology},
  • V. Montero-Alejo, G. Corzo, +9 authors R. Perdomo-Morales
  • Published 2017
  • Biology, Medicine
  • Developmental and Comparative Immunology
  • ABSTRACT Beta_defensin have been solely found in vertebrates until &bgr;‐defensin‐like peptides were described as transcript isoforms in two species of Panulirus genus. They were considered as putative antimicrobials since their biological activity have not been demonstrated. Here we purified and characterized a defensin‐like peptide from the hemocytes of spiny lobster P. argus, hereafter named panusin. Structurally, panusin presents a cysteine‐stabilized &agr;/&bgr; motif, and is prone to form… CONTINUE READING
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