Pantoprazole does not interact with the pharmacokinetics of carbamazepine.

@article{Huber1998PantoprazoleDN,
  title={Pantoprazole does not interact with the pharmacokinetics of carbamazepine.},
  author={Reiner I. Huber and Harald Bliesath and Mich{\'e}lle Chalbaud Biscaia Hartmann and Volker W. Steinijans and Herren U. J. Koch and Hermann Josef Mascher and Wilhelm Wurst},
  journal={International journal of clinical pharmacology and therapeutics},
  year={1998},
  volume={36 10},
  pages={
          521-4
        }
}
OBJECTIVE Pantoprazole is a H+/K+-ATPase inhibitor with a minimized potential of interaction with the cytochrome P450 system. Imidazole derivatives such as cimetidine and omeprazole have been shown to markedly interact with carbamazepine, a major anticonvulsant with a narrow therapeutic range. Therefore, the influence of steady-state pantoprazole on the pharmacokinetics of carbamazepine was investigated. SUBJECTS AND METHODS N = 20 healthy volunteers (12 male/8 female) completed a double… CONTINUE READING

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Intravenous pantoprazole: a new tool for acutely ill patients who require acid suppression.

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  • 2000
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