Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection.

@article{Calabrese2000PantoprazoleAA,
  title={Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection.},
  author={Cristina Calabrese and Giulio Di Febo and Alessandra Areni and Carlo Scialpi and Guido Biasco and Mario Miglioli},
  journal={Alimentary pharmacology & therapeutics},
  year={2000},
  volume={14 12},
  pages={
          1613-7
        }
}
BACKGROUND Azithromycin is an acid-stable macrolide that achieves remarkably high concentrations in gastric tissue, persisting above the MIC90 for Helicobacter pylori over a period of 5-days, after a single 500 mg oral dose. AIM To evaluate and compare the efficacy, safety, and tolerability of two eradicating regimens of pantoprazole, azithromycin and tinidazole. METHODS A total of 100 consecutive symptomatic H. pylori-positive patients received pantoprazole 40 mg b.d. for 1 week, and were… CONTINUE READING
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